Content Outline and Competencies:

I. Study Strategies

A. Identify course expectations by reading the syllabus.

B. Apply a reading-studying technique that includes pre-reading, reading with notetaking or textbook marking, and reviewing.

C. Write meaningful notes in class using an established system (Cornell or 2     column format, concept mapping).

D.  Apply cognitive strategies to learning chemistry concepts including elaboration, distinction, appropriate retrieval, and over-learning.

E.  Apply effective test-taking strategies.

F.  Utilize campus resource centers (Academic Achievement Center and Science Resource Center).

G.  Demonstrate the operation of a non-graphing calculator for basic mathematical operations.

H. Establish a professional relationship with the instructor and communicate difficulties appropriately.

I. Demonstrate an awareness of the student code of conduct.

II. Matter and Measurement

A.  Express numbers using scientific notation.

B.  Determine the number of significant figures in measured numbers.

C.  Calculate answers to the correct number of significant figures.

D.  State the basic units of measurement for length, mass, volume and temperature in the SI system.

E.  Solve problems using dimensional analysis, including conversion of units.

F.  Solve problems involving density.

III. Physical and Chemical Changes

A.  Distinguish among the three states of matter (solid, liquids, and gases).

B.  Classify matter according to its composition: elements, compounds and mixtures.

C.  Distinguish between physical and chemical properties and physical and chemical changes.

D.  Recognize and illustrate the law of conservation of mass and the law of conservation of energy.

IV. Atomic Theory and the Periodic Table

A.  Explain concepts of basic atomic theory.

B.  Describe the properties of protons, neutrons and electrons.

C.  State how elements are defined by their numbers of protons.

D.  Explain the periodic law and the arrangement of the periodic table.

E.  Demonstrate how main group elements form ions and predict charges that ions will form.

F.  Recognize that neutron variation leads to isotopes.

V. Molecules and Compounds

A.  Demonstrate the meaning of chemical formulas.

B.  Describe how atomic elements, molecular elements, molecular compounds and ionic compounds appear at the molecular level.

C.  Name ionic compounds, molecular compounds and acids using the appropriate nomenclature.

D.  Write the correct formulas for ionic and covalent compounds.

VI. Chemical Composition

A.  Calculate the molecular mass of a compound from its formula.

B.  Solve problems relating the mass of a compound to the number of moles of a compound.

C.  Solve problems relating the mass of a compound to the number of molecules.

VII. Chemical Reactions

A.  Identify reactants and products in chemical reactions.

B.  Write a balanced chemical equation given the reactants and products.

C.  Predict the products of precipitation reactions.

D.  Write balanced complete and net ionic equations.

VIII. Lewis Structures

A.  Determine the number of valence electrons for an atom and write its Lewis symbol.

B.  Draw Lewis structures for atoms, ions and covalent compounds.

C.  Predict the shapes of molecules using VSEPR theory.

D.  Predict molecular polarity from the molecular shape and the electronegativity of the atoms involved.

IX. Solutions

A.  Define terms associated with solutions.

B.  Describe the solution process for electrolytes and nonelectrolytes in water.

C.  Calculate the percent concentration of a solute in a solution and use percent concentration to calculate the amount of solute or solution.

D.  Calculate the molarity of a solution and use molarity as a conversion factor to calculate the moles of solute or the volume needed to prepare a solution.

E.  Calculate the concentration or volume of a solution before or after a dilution.

Content Outline and Competencies:

I. Scientific Method of Learning

A. Investigate natural phenomena using scientific methodology.

1. Make observation

2. Construct hypotheses

3. State laws

4. Articulate theories

5. Develop models

B. Summarize information about risks and benefits relative to a scientific issue, and compare risks and benefits.

C. Analyze scientific claims using the characteristics of critical thinking. 

1. Falsifiability

2. Logic

3. Replicability

4. Sufficiency

II. Atomic Theories of Matter

A. Describe the atomic theories of:

1. Democritus

2. Lavoisier

3. Proust

4. Dalton

B. List the four postulates of Dalton's atomic theory.

C. Explain the laws of:

1. Conservation of mass

2. Definite proportions

3. Multiple proportions

D. Locate the fundamental parts of an atom.

E. Describe the scientific process leading to the modern understanding of the atom, including experiments and/or theories of:

1. John Dalton

2. J.J. Thomson

3. Eugene Goldstein

4. Robert Millikan

5. Ernest Rutherford

6. Niels Bohr

F. Determine the number of protons and electrons in an atom of any element using the periodic table.

G. Describe similarities and differences between the Bohr model of the atom and the quantum mechanical model.

H. Identify the charge and relative masses of the proton, the neutron and the electron.

I. List similarities or differences between elements in families and periods in the modern periodic table.

III. Atomic Nuclei and Nuclear Reactions

A. Calculate the number of neutrons, the number of protons or the nucleon number in an atom, given any two of these.

B. Supply the missing nuclide in any nuclear reaction.

C. Describe the symbols and general characteristics for:

1. Alpha radiation

2. Beta radiation

3. Gamma radiation

D. Identify nuclides that are isotopes.

E. Describe the relative mass and charge of subatomic particles.

1. Protons

2. Neutrons

3. Electrons

4. Alpha particles

5. Beta particles

6. Gamma rays

F. Distinguish between nuclear fission and fusion.

G. Calculate the age of an artifact given the fraction decrease in activity and the half-life of the isotope undergoing radioactive decay.

H. List the principal sources of radiation.

I. Describe the use of radioisotopes in medicine.

1. List commonly used radioisotopes.

2. Match the isotopes with procedures in which they are used.

J. Explain what is meant by "nuclear winter."

IV. Chemical Bonds

A. Distinguish between compounds with different types of chemical bonds.

1. Ionic bonds

2. Polar covalent bonds

3. Nonpolar covalent bonds

B. Calculate simple combining ratios of atoms.

C. Draw electron dot symbols for the first 20 elements in the periodic table.

D. Construct structural formulas for simple covalent compounds given the molecular formula.

E. Determine the number of bonds a nonmetal element will form using the periodic table.

F. Predict the shape of simple molecules using the VSEPR theory.

G. Describe transfer of electrons between atoms that form ionic bonds.

H. Describe the sharing of electrons between atoms that form covalent bonds.

I. Explain the polarity of covalent bonds using electronegativity differences.

J. Explain the relationship between valence electrons and molecular shape using VSEPR theory.

K. Describe situations where dipole forces, hydrogen bonds and dispersion forces are important.

V. Chemical Compounds, Formulas and Reactions

A. Write formulas and names for ionic compounds given positive and negative ions.

B. Write the name given the formula of a covalent compound.

C. Convert between mass and number of moles of a substance given the formula.

D. Balance simple chemical equations.

E. Calculate mole ratios of reactants and products in a balanced chemical equation.

VI. Acids and Bases

A. Describe the properties of acids and bases.

B. Match pH values and acid or base character.

C. Describe acid-base chemistry as it applies to acid rain and antacids.

VII. Oxidation and Reduction Reactions

A. Identify substances that are oxidized or reduced.

B. List applications of reducing and oxidizing agents.

C. Describe oxidation and reduction in electrochemical cells, batteries and corrosion.

D. Describe the role of oxidation and reduction in biological processes.

VIII. Gases

A. Describe the kinetic theory of gases.

B. Describe the units of measurement used for pressure and convert from one unit to another.

C. Define terms associated with gases and pressure.

IX. Solutions

A. Define solute and solvent, and describe the formation of a solution.

B. Calculate the percent concentration of a solute in a solution, and use percent concentration to calculate the amount of solute or solution.

C. Calculate the molarity of a solution and use molarity as a conversion factor to calculate the moles of solute or the volume needed to prepare a solution.

Optional Content Outline and Competencies

X. Polymers

A. Match a given monomer with the polymer from which it is produced.

B. Describe the general types of polymers.

1. Addition

2. Condensation

3. Cross linked

C. List advantages and problems associated with use of plastics.

XI. Air

A. Describe the layers of the atmosphere and their chemical composition.

B. Describe the nitrogen and oxygen cycles.

XII. Water

A. Describe the properties of water.

B. Sketch the water cycle.

C. Describe the sources and types of water contamination.

XIII. Energy

A. Accurately use the units and terms of energy.

B. State the first and second laws of thermodynamics.

C. Give examples of effects of the laws of thermodynamics.

D. List sources of energy.

1. Fossil fuels

2. Nuclear

3. Solar

4. Hydroelectric

E. Describe the advantages and disadvantages of each energy source.

Lab:

I. Safety and Measurements

A. Work safely and effectively in performing laboratory experiments.

B. Follow written directions accurately.

C. Perform techniques used in laboratory experiments.

D. Acquire data using balances and volumetric equipment.

E. Estimate and verify the mass of an object.

F. Estimate and verify the length of an object.

G. Calculate the average of a series of data to the correct number of significant figures.

H. Write data and measurements to the correct number of significant figures.

II. The Scientific Method

A. Make verifiable observations.

B. Distinguish the role of a hypothesis and that of a null hypothesis.

C. Conduct a successful experiment.

D. Summarize the roles of variables and controls in an experiment.

E. Collect data in an organized fashion.

F. Illustrate the keys to successful analysis.

III. Data Measurement

A. Describe the metric system.

B. Calculate unit conversions.

C. Summarize techniques for obtaining accurate measurements.

IV. Periodic Table

A. Group elements that have similar chemical properties.

B. Separate groups of elements by observing variations in chemical behavior.

C. Verify the organization of the modern periodic table using experimental data and values from reference sources.

V. Electron Configuration

A. Observe energy emitted from different energy levels when salt compounds are ignited.

B. Summarize what produces different colors in fireworks.

VI. Chemical Reactions

A. Predict the results of qualitative tests for ions that are based on solubility.

B. Describe the solubility of sodium, potassium, ammonium, nitrate and acetate ions.

C. Recognize balanced chemical equations.

D. Test for the presence of fluoride ions in mouth rinses.

VII. Acids and Bases

A. Review the properties and reactions of acids and bases.

B. Relate acid/base properties to common household properties.

Content Outline and Competencies:

I. Matter and Measurements

A. Write the names and abbreviations for the metric (SI) units used in measurements of length, volume and mass.

B. Determine the number of significant figures in measured numbers.

C. Adjust calculated answers to the correct number of significant figures.

D. Write a metric equality using the numerical values, symbols, and prefixes.

E. Convert from one unit to another using one or more conversion factors.

F. Calculate the density or specific gravity of a substance and use the density or specific gravity to calculate the mass or volume of a substance.

G. Calculate the molar mass and use molar mass to convert between mass and moles given the chemical formula of a substance.

H. Describe the units of measurement used for pressure and temperature and be able to convert from one unit to another.

II. Atomic Theory and the Periodic Table

A. Write the correct symbol or element name when given the name or symbol of an element.

B. Classify elements using the periodic table.

C. Describe the electrical charge, mass (amu) and location in an atom for a proton, neutron and electron.

D. State the number of protons, neutrons, and electrons or vice versa given the atomic number and mass number of an isotope.

E. Write the electron arrangement and use it to explain the periodic law given the name or symbol of one of the first 20 elements in the periodic table. Describe the electromagnetic spectrum, including relationships between wavelength, frequency, and energy.

F. Write the electron dot structure for a representative element or ion using the periodic table.

G. Write the symbols of the simple ions for the representative elements using the octet rule.

III. Chemical Bonding, Chemical Nomenclature, and Molecular Structure

A. Demonstrate an understanding of inorganic chemistry.

1. Write the correct formula for an ionic compound using charge balance.

2. Write the formula of an ionic compound given the name and; given the name, write the correct formula.

3. Diagram the electron-dot structure for a covalent molecule.

4. Write the correct formula of a covalent compound from its name; name a covalent compound given the formula.

5. Write a formula of a compound containing a polyatomic ion; given the formula of a compound containing a polyatomic ion, write the correct name.

6. Classify a bond as nonpolar covalent, polar covalent or ionic using electronegativity.

B. Demonstrate an understanding of organic chemistry.

1. From its properties, classify a compound as organic or inorganic.

2. Draw the complete and the condensed structural formula for an alkane.

3. Write the names and structural formulas of the first ten unbranched alkanes.

4. Use the IUPAC system to write the names of branched-chained alkanes.

5. Write the structural formulas of alkanes and their isomers.

6. Name a cycloalkane and draw both the structural and geometric formulas.

7. Describe the bonding in benzene, name aromatic compounds, and write their structural formulas.

8. Classify alkanes, alkenes, alkynes, and aromatics according to their functional groups.

9. Give the name for a haloalkane or draw the structural formula from the name.

10. Write the IUPAC names for the structural formulas of alkenes, cycloalkenes, and alkynes or write their structural formulas from their names.

11. Write the names and structural formulas of alkenes that have cis-trans isomers.

12. Write the structural formulas and names for the products of the addition reactions of alkenes.

13. Write the structure of common substituents given the name and vice versa.

14. Identify the following functional groups: alcohols, thiols, ethers, aldehydes, ketones, carboxylic acids, esters, amines, amides, sulfides, disulfides, phosphates, carboxylates, and acetals.

15. Classify alcohols and amines as primary, secondary, or tertiary.

IV. Aqueous Solutions and Aqueous Reactions

A. Describe hydrogen bonding in solutions.

B. Define solute and solvent and describe the formation of a solution.

C. Describe the solution process for electrolytes and nonelectrolytes in water.

D. Convert between mass, moles, and equivalents.

E. Define solubility and distinguish between an unsaturated and a saturated solution.

F. Identify an insoluble salt.

G. Calculate the percent concentration of a solute in a solution and use percent concentration to calculate the amount of solute or solution.

H. From its properties, identify a mixture as a solution, colloid, or suspension.

I. Calculate the molarity of a solution and use molarity to calculate the moles of solute or the volume needed to prepare a solution.

J. Complete and balance precipitation reactions.

K. Write a balanced equation to show the deionization or dissociation of electrolytes (salts) in water.

L. Describe acids and bases using the Arrhenius and Brønsted-Lowry concepts.

M. Use the ion product of water to calculate the [H₃O⁺] and [OH^-] in a solution.

N. Calculate pH from [H₃O⁺] and given the pH, calculate [H₃O⁺] and [OH^-] of a solution.

O. Write an equation for the ionization of strong and weak acids and bases.

P. Describe the preparation of a dilute solution given the molarity or percent concentration of the solution.

Q. Write a balanced equation for the neutralization reaction between an acid and a base.

R. Describe the role of buffers in maintaining the pH of a solution.

S. Determine the effect on equilibrium concentrations when reaction conditions change.

T. Describe the solubility of organic compounds with various functional groups in water.

V. Biological Molecules

A. Classify carbohydrates according to their structure, shape, and function.

1. Locate chiral centers in organic molecules.

2. Classify carbohydrates as monosaccharides, disaccharides, or polysaccharides.

3. Classify a monosaccharide as an aldose or ketose and indicate the number of carbon atoms.

4. Draw the corresponding mirror image and indicate whether it is a D or L isomer given a Fischer Projection of a monosaccharide.

5. Draw the open chain structures for D-glucose, D-ribose, and D-fructose.

6. Identify alpha and beta structures in Haworth projections for monosaccharides.

7. Describe polysaccharides, alpha and beta bonds, as well as the monosaccharide units in polysaccharides.

8. Classify the type of glycosidic bond given the Haworth structure of a disaccharide. For the disaccharides maltose, lactose, and sucrose, identify the monosaccharides and type of glycosidic bonds.

B. Classify lipids according to their structure, shape, and function.

1. Identify a fatty acid as saturated or unsaturated.

2. Describe the structure and functional groups of waxes, fats, and oils.

3. Draw the structure of the product from the reaction of a triglyceride with hydrogen, an acid or a base, or an oxidizing agent.

4. Write the products of a saponification reaction.

C. Classify amino acids, proteins, and enzymes according to their structure, shape, and function.

1. Write the general structural formula of an amino acid and, given the structural formula of the R group, be able to classify it as nonpolar,polar, acidic, or basic based upon their R group side chains.

2. Write the structure of adipeptide given the structure of two amino acids.

3. Distinguish between the primary, secondary, tertiary, and quaternary structures of a protein.

4. Describe denaturation of proteins.

5. Compare the various functions of proteins

6. Describe how an enzyme catalyzes a biochemical reaction.

7. Discuss factors that enhance and inhibit enzyme activity.

D. Classify nucleic acids according to their structure, shape, and function..

1. Identify the parts of nucleotides and nucleic acids.

2. Form a nucleic acid from nucleotides.

3. Describe the unique structural features of DNA.

4. Specify the roles of RNA in protein synthesis.

E. Describe metabolism in terms of chemical reactions that occur.

1. Describe features of metabolic reactions.

2. Distinguish the high-and low-energy forms of metabolically relevant nucleotides.

3.Describe the products of food molecule hydrolysis contrasting the digestion of carbohydrates, lipids, and proteins.

VI. Organic and Inorganic Equations

A. Write a balanced chemical equation from the formulas or names of the reactants and products for a reaction.

B. Define oxidation and reduction as it occurs in both inorganic and organic compounds.

C. Describe some forms of energy.

D. Describe the energy in exothermic and endothermic reactions; describe the function of a catalyst.

E. Calculate the amount or mass of product formed given the amount or mass of a reactant.

F. Describe factors affecting the rate of reaction.

G. Write balanced chemical equations for the combustion of hydrocarbons.

H. Distinguish between complete and incomplete combustion and write balanced equations for each.

I. Write the reactions and/or products for the oxidation and reduction of alcohols, aldehydes, and ketones.

J. Write equations for the formation esters (esterification) and amides (amidation).

VII. Solids, Liquids, and Gases

A. Identify the physical state of a substance and describe the changes of state between solids, liquids, and gases.

B. Describe the kinetic theory of gases.

C. Calculate and describe important gas laws.

VIII. Laboratory Practices

A. Demonstrate a knowledge of safe laboratory practices, including appropriate dress, handling of chemicals, and disposal of chemical waste.

B. Explain the appropriate use of common laboratory equipment and perform laboratory measurements.

C. Graph data and correctly use data obtained from graphs.

D. Use significant figures properly in all measurements and calculations.

E. Carry out experiments according to directions.

F. Record evidence of chemical and physical properties and changes.

IX. Laboratory Work

A. Demonstrate appropriate ability to make measurements.

B. Solve chemical reactions by balancing and report observations.

C. Identify correct means of performing calculations and compute correct answers.

D. Name chemical compounds correctly and explain rules for nomenclature.

Content Outline and Competencies:

Content Outline and Competencies:

I. Describe Matter and Its Measurement, Including Calculations Done on
Measurements
   A. Distinguish among the three states of matter (solid, liquids and
gases).
   B. Distinguish among elements, compounds and mixtures.
   C. Distinguish between physical and chemical properties and physical
and chemical changes.
   D. State the basic units of measurement for length, mass, volume and
temperature in the SI system.
   E. Give the numerical equivalent of selected SI prefixes.  
   F. Convert temperatures between Fahrenheit, Celsius and Kelvin scales.
   G. Express numerical answers to the correct number of significant
figures.
   H. Solve problems using dimensional analysis, including conversion of
units.
   I. Solve problems involving density.

II. Demonstrate an Understanding of Basic Chemical Nomenclature
   A. Write the name and symbol for selected elements.
   B. Write the name and symbol for selected polyatomic ions.
   C. Compare and contrast molecular compounds and ionic compounds.
   D. Write names and formulas for the following types of compounds: ionic
compounds, binary molecular compounds and acids.

III. Explain Concepts of Basic Atomic Theory and Relate the Theory to the
Periodic Table
   A. Recall the basic ideas in Dalton's atomic theory.
   B. Summarize the experiments of J.J. Thomson, Robert Millikan and
Ernest Rutherford that characterized the structure of the atom.
   C. Describe atoms in terms of electrons, protons and neutrons.
   D. Given the isotopic masses and fractional abundances for a naturally
occurring element, calculate its atomic weight.
   E. Identify the following areas of the periodic table: metals,
nonmetals and metalloids; main groups, transition metals, inner transition
metals; alkali metals, alkaline earth metals, halogens and noble gases.
   F. Describe the formation of cations and anions and use the periodic
table to predict the charges of monoatomic ions.

IV. Write Chemical Reactions and Solve Problems Involving Chemical
Stoichiometry
   A. Calculate the molecular mass of a compound from its formula.
   B. Solve problems relating the mass of a compound to the number of
moles of a compound.
   C. Solve problems relating the mass of a compound to the number of
molecules.
   D. Calculate the percent composition of a compound from its formula.
   E. Determine the empirical formula of a compound from its percent
composition.
   F. Determine the molecular formula of a compound from its empirical
formula and molecular mass.
   G. Write a balanced chemical equation given the reactants and
products.
   H. Predict the product of the combustion reactions of hydrocarbons and
simple compounds having C, H and O.
   I. Identify chemical reactions by type: combination, decomposition,
combustion.
   J. Solve problems relating grams and moles of substances in balanced
chemical equations.
   K. Calculate theoretical yield and percent yield when actual yield is
given.
   L. Recognize the limiting reagent in a reaction and do calculations
with limiting reagent.

V. Describe the Nature of Aqueous Solutions and Reactions Occurring in
Aqueous Solution
   A. Explain how to make solutions of given concentration.
   B. Explain how to dilute solutions to a specified volume or
concentration.
   C. Solve solution stoichiometry problems.
   D. Distinguish among strong, weak and nonelectrolytes in solution.
   E. Write balanced complete and net ionic equations.
   F. List the common acids and bases and classify each as a strong or
weak electrolyte.
   G. Assign oxidation numbers to atoms in molecules and ions.
   H. Recognize oxidation-reduction reactions and identify oxidizing and
reducing agents.
   I. Balance simple oxidation-reduction reactions by the half-reaction
method.

VI. Apply Concepts of Thermochemistry to Physical and Chemical Changes
   A. Recognize and illustrate the law of conservation of energy.
   B. Distinguish between a system and its surroundings and describe the
energy changes in a system and its surroundings during a given reaction.
   C. State the first law of thermodynamics.
   D. Solve problems involving enthalpies for physical and chemical
changes.
   E. Solve calorimetry and heat capacity problems.
   F. Calculate enthalpy changes using Hess' law and measured enthalpies
of reaction.
   G. Calculate standard enthalpies of reaction from standard enthalpies
of formation.
   H. Determine the enthalpy of reaction using bond energies.

VII. Describe the Electronic Structure of Atoms and Relate the Electronic
Structure to Atomic Properties
   A. Solve problems relating frequency, wavelength and energy of
electromagnetic radiation.
   B. Explain the essential feature of Planck's quantum theory.
   C. Discuss how line spectra give evidence of energy quantization.
   D. Describe the wave mechanical model of the atom.
   E. Describe s and p orbitals and recognize d orbitals.
   F. Write a set of quantum numbers for any particular electron.
   G. Write the electron configuration of elements up to atomic number
57.
   H. Write electron configurations for ions of main group and transition
elements.
   I. Relate position on the periodic table to electron configuration and
quantum numbers.
   J. Describe the scientific contributions of Planck, Einstein, de
Broglie, Bohr, Schrodinger, Heisenberg, Pauli and Mendeleyev.
   K. Apply Periodic Trends in atomic radii to predict relative size of an
atom.
   L. Predict relative first ionization energies from periodic trends.
   M. Explain the observed changes in value of the successive ionization
energies for a given atom.
   N. Describe the periodic trends in metallic and nonmetallic behavior.
   O. Describe the general differences in chemical reactivity between
metals and nonmetals. 

VIII. Demonstrate an Understanding of Chemical Bonding and its Application
to Molecular Structure
   A. Determine the number of valence electrons for an atom and write its
Lewis symbol.
   B. Recognize when the octet rules applies to the arrangement of
electrons in the valence shell.
   C. Predict the relative size of anions and cations formed from an
atom.
   D. Use electronegativity differences between bonding atoms to classify
bonds as non-polar, polar covalent or ionic.
   E. Draw Lewis structures for atoms, ions and covalent compounds,
recognizing when multiple bonds, resonance structures, expanded valence
shells, incomplete valence shells and odd electrons are needed.
   F. Relate the number of electron pairs in the valence shell of an atom
in a molecule to the geometrical arrangement around that atom.
   G. Predict molecular geometry using the VSEPR model.
   H. Predict whether a molecule can have a net dipole moment from the
molecular shape and the electronegativity of the atoms involved.
   I. Describe covalent bonding using valance bond theory.
   J. Describe sp, sp2 and sp3 hybrid orbitals.
   K. Describe the bonding in a double and triple bond.

IX. Describe the Properties of Solids, Liquids and Gases and Relate Those
Properties to Intermolecular Forces
   A. Compare and contrast gases, liquids and solids.
   B. Convert between torr, mm Hg, standard atmosphere and Pascal.
   C. Demonstrate an understanding of the gas laws (Charles', Boyle's
ideal, etc.) by working problems with them.
   D. List the points of the kinetic molecular theory and describe how
this theory explains the common gas laws.
   E. Work stoichiometry problems involving gases and the gas laws.
   F. Describe how the relative rates of diffusion and effusion of two
gases depend on their molar masses (Graham's law).
   G. Describe how a real gas differs from an ideal gas.
   H. Employ the kinetic molecular model to explain the differences
between the gas, liquid and solid states.
   I. Recognize where dipole-dipole forces, hydrogen bonding and London
dispersion forces are important.
   J. Qualitatively explain the relationship between intermolecular forces
and properties of liquids and solids.
   K. Draw a phase diagram of a substance given proper data and use a
phase diagram to predict the phases present at a given temperature and
pressure.
   L. Given heating/cooling curves, calculate the heat associated when a
given substance changes from one condition to another.
   M. Compare and contrast crystalline and amorphous solids.
   N. Categorize crystalline solids as ionic, molecular, covalent network
and metallic solids.

Content Outline and Competencies:

Content Outline and Competencies:

I. Work in the Laboratory in Accordance with Good Laboratory Practices

A. Dress in an appropriate manner as to promote safety in the laboratory, wearing a lab coat and goggles when anyone is working with chemicals in the laboratory.

B. Follow written directions accurately.

C. Work safely and effectively, using equipment and chemicals carefully and correctly.

D. Demonstrate use of required techniques.

E. Dispose of waste products in a proper manner.

II. Gather and Record Qualitative and Quantitative Data Accurately

A. Acquire data using balances and volumetric glassware.

B. Make and record visual observations.

C. Use computers, when appropriate, as data acquisition tools.

D. List or describe experimental assumptions made and any deviations from the written experimental procedures.

III. Handle and Evaluate Data in Logical, Productive and Meaningful Way

A. Create notebooks and laboratory reports that are clear, understandable and accurate.

B. Display computer data in a spreadsheet or graphically, as appropriate.

C. Correlate observations with chemical or physical processes.

D. Carry out suitable calculations with quantitative data, recognizing when data and calculations are within a reasonable range.

E. Use observations of experimental data to present relevant conclusions pertaining to the experimental procedure.

IV. Correlate Laboratory Work with Principal Topics in Chemistry I Lecture

A. Measurements

B. Chemical reactions and stoichiometry

C. Thermochemistry

D. Gas laws

Content Outline and Competencies:

I. Mixtures and Their Characteristics

A. Describe the processes by which solutes and solvents interact in forming solutions. Include terms about the nature of particles, the various forces and energy involved.

B. Solve concentration problems with molarity, mass percent, mole fraction, molality and ppm.

C. Solve problems with Henry's law.

D. Describe temperature effects on solubility.

E. Explain qualitatively the colligative properties, vapor pressure lowering, boiling point elevation and freezing point depression, and work quantitative problems.

F. Describe the process of osmosis and some applications and solve quantitative problems.

G. Describe how the colligative properties of solutions of electrolytes differ from those of solutions of non-electrolytes.

H. Describe the characteristics of colloids and give examples.

II. Chemical Kinetics and Interpretation of Chemical Reactions

A. Discuss the effect of concentration, temperature, catalysis and physical state upon rate of reaction.

B. Distinguish between average rate and instantaneous rate.

C. Describe the two types of rate laws (differential and integrated).

D. Distinguish between first and second order reactions.

E. Explain why a rate law must be determined experimentally.

F. Discuss and apply the method of initial rates.

G. Discuss the relationship between half-life equations and reaction order.

H. Use graphs and equations to determine the order of a reaction.

I. Draw a reaction profile to explain the progress of a reaction.

J. Describe the collision model and discuss the temperature dependence of reaction rates.

K. Define and calculate activation energy.

L. Discuss reaction mechanisms and explain the rate-determining step.

M. Explain the effect of a catalyst on a chemical reaction.

III. Chemical Equilibria and Applications

A. Explain how the terms reversible reaction and dynamic equilibrium are related.

B. Write the general equilibrium constant expression and explain its significance.

C. Explain why the concentrations of pure liquids and solids are never used in equilibrium constant expressions.

D. Show how the numerical value of the equilibrium constant changes when the stoichiometric coefficients are changed or the reaction is reversed.

E. Explain the differences between the terms Kc and Kp and the relation of either to Qc.

F. Explain the difference between an equilibrium position and equilibrium constant.

G. Given Keq and initial concentration of reactants and/or products, calculate the final concentrations of reactants and/or products.

H. List the external factors that can affect equilibria.

I. Explain how changes in temperature, pressure, volume or concentration affect the equilibrium position for a chemical reaction.

J. Describe the effect of a catalyst on a system as it approaches equilibrium.

IV. Chemical Equilibria in Aqueous Solutions

A. Explain the similarities and differences between terms such as: Ka and Kb, pH and pOH, and pKa and pKb.

B. Apply Brønsted-Lowry acid-base concepts to determine the relative strength of acids and their conjugate bases.

C. Name and list the common strong acids (HCl, HBr, HI, HNO3, H2SO4 and HClO4) and strong bases (i.e., any hydroxide base).

D. Relate [H+] and [OH-], pH and pOH. Calculate the pH for solutions of strong acids and bases.

E. Identify a weak acid or base and write a chemical equation to represent its ionization. Set up an equation for determining its ionization constant expression (Ka and Kb).

F. Calculate from appropriate data, ionization constants (Ka or Kb), concentration of the non-ionized acid or base, the concentration of ions in aqueous solution, the pH and the percent dissociation.

G. Relate acid strength to Ka and base strength to Kb.

H. Explain why certain salts give acidic, basic or neutral solutions and show how to calculate the pH of these solutions.

I. Describe the ionization of a polyprotic acid in aqueous solution.

J. Explain how bond strength and polarity affect acid-base properties.

K. Identify the Lewis acid and base in a chemical reaction.

L. Describe the effect of common ions on the ionization of weak acids or bases and calculate the concentration of species present in solutions of weak acids or bases with their common ion.

M. Explain why pure water cannot resist changes in pH as well as a buffered solution.

N. Use the Henderson-Hasselbach equation to determine the pH of a buffered solution.

O. Calculate the pH of a buffer solution from concentrations of the buffer components and a value of Ka and Kb, and describe how to prepare a buffer having a specific pH.

P. Determine the changes in pH of a buffer solution that result from addition of acids or bases.

Q. Determine the volume of a solution of known concentration required to titrate another solution of known volume and concentration.

R. Determine the concentration of a solute in a solution by titrating it against a known amount of another substance.

S. Sketch a titration curve for the titration of:

1. Strong acid with a strong base

2. Weak acid with a strong base

3. Weak base with a strong acid

4. Polyprotic acid or base

T. Write an equation to express the relationship between a solid solute and its constituent ions in a saturated solution.

U. Calculate the Ksp from molar solubility and molar solubility from Ksp.

V. Calculate the effect of a common ion on the molar solubility of a salt.

W. Predict whether precipitation will occur when salt solutions are mixed and determine the concentration of ions remaining in solution after precipitation.

X. Solve chemical equilibrium problems involving complex ions.

V. Thermodynamics in Chemical and Physical Processes

A. Explain the similarities and differences between such terms as enthalpy, entropy and free energy.

B. Apply the first, second and third law of thermodynamics to the analysis of chemical and physical processes.

C. Predict whether the entropy change in a given process is positive, negative or near zero.

D. Use data tables to determine enthalpy, entropy and free energy changes.

1. Use enthalpies of formation to calculate ∆H for a reaction (Hess’s Law).

2. Use standard molar entropies to calculate ∆S for a reaction.

3. Use Gibbs free energies of formation to calculate ∆G for a reaction.

E. Explain how ∆H, ∆S and ∆G are related to reaction spontaneity.

F. Explain how a knowledge of ∆H, ∆S and ∆G allows one to predict the conditions under which a reaction will occur.

G. Describe the relationship between the standard free energy of reaction and the equilibrium constant. Calculate Keq for a chemical reaction from ∆H°f and S° or ∆G°f.

H. Calculate ∆G for a chemical reaction that occurs under nonstandard conditions.

VI. Electrochemical Reactions and Applications

A. Describe oxidation-reduction reactions as electron loss and electron gain.

B. Using the half-reaction method, balance half-reactions in acidic and/or basic solutions to complete an oxidation-reduction equation.

C. Describe the components and operation of voltaic and electrolytic cells.

D. Using standard half-cell potentials, calculate cell potentials for both voltaic and electrolytic cells and make predictions about reaction spontaneity.

E. Using a table of standard reduction potentials, predict whether a selected reaction will occur (e.g., Will copper replace silver ion in solution?).

F. Explain the similarities and differences between terms such as anode and cathode, voltaic cell and electrolytic cell, electromotive force and voltage.

G. Relate cell potential, free energy change and equilibrium constant.

H. Using the Nernst equation, calculate the cell potential for reactions occurring under nonstandard conditions.

I. Solve stoichiometry problems involving electrolytic cells.

J. Describe practical applications for voltaic and electrolytic cells (batteries, corrosion and commercial electrolytic cells).

VII. Nuclear Reaction Processes

A. Explain the similarities and differences between such terms as alpha, beta and gamma radiation; binding energy and mass defect; fission and fusion.

B. Review and describe the composition of the nucleus.

C. Name the different types of radioactive decay (e.g., alpha decay) and describe the characteristics of each.

D. Write balanced equations for radioactive decay processes.

E. Calculate the rate of radioactive decay, the half-life or the number of atoms or moles in a sample of a radioactive nuclide if two of the three terms are known.

F. Write equations for nuclear transformation reactions.

G. Describe some of the practical and beneficial uses of radioisotopes.

H. Describe the processes of nuclear fission and fusion and discuss the problems with using either process as a source of energy.

I. Describe the difference between commonly used units of radiation (i.e., curie, rad, rem).

VIII. Critical Thinking Skills

A. Solve algebraic problems given new data.

B. Apply appropriate chemical theories in new situations to explain and predict.

C. Recognize and explain chemical phenomena in everyday occurrences.

Content Outline and Competencies:

Content Outline and Competencies:

I. Students Will Work in the Laboratory in Accordance with Good Laboratory Practices

A. Dress appropriately on lab days, wearing long pants and shoes will enclosed toes. Wear a lab coat and goggles when anyone in the laboratory is using chemicals.

B. Follow written directions accurately.

C. Work safely and effectively, using equipment and chemicals carefully and correctly.

D. Demonstrate use of required techniques.

E. Obtain samples from stock reagents that are correct substance, concentration and sample size.

F. Dispose of waste products appropriately.

II. Students Will Gather and Record Qualitative and Quantitative Data Accurately

III. Students Will Handle and Evaluate Data in Meaningful Ways

A. Keep notebooks and worksheets that are neat, clean, understandable and accurately represent work done.

B. Display computer data in a spreadsheet or graphically, as is relevant.

C. Correlate observations with chemical reactions.

D. Carry out suitable calculations with quantitative data, recognizing when data and calculations are within a reasonable range.

E. Use applicable theories to draw experimental conclusions and explain observations.

IV. Students Will Correlate Laboratory Work with Principal Topics in Chemistry II, Lecture, Including:

A. Chemical kinetics

B. Chemical equilibria

C. Acid-base chemistry

D. Electrochemical reactions

Content Outline and Competencies:

I.  Classification of Compounds as Bond Structures, Shape and Functional Groups

A. Describe the structure of the atom and write the electronic structure of the atoms.

B. Compare and contrast related terms such as ionic and covalent bonding, sp, sp2 and sp3 hybrid orbitals.

C. Use VSEPR theory to describe the molecular geometry and shape.

D. Use electronegativity and molecular shape to describe polar and nonpolar molecules.

E. Draw Lewis structures of selected compounds.

F. Recognize and draw all of the common functional groups of organic compounds.

G. Solve problems and recognize the type of hybrid orbital of the C or N atom of each functional group.

H. Correctly define, explain and use the terms and concepts related to bonding and geometry.

II. Alkanes and Cycloalkanes

A. Name and draw structures for alkanes and cycloalkanes by the IUPAC system.

B. Predict and explain the general trends in the physical properties of alkanes.

C. Draw and name the structural isomers for alkanes.

D. Show the conformation of small alkanes and the cis-trans isomerism of cycloalkanes.

E. Correctly define, explain and use the terms and concepts related to alkanes and cycloalkanes.

III. Alkenes and Alkynes

A. Use the IUPAC system to name and draw selected alkenes and alkynes.

B. Discuss the bonding and electronic structure of alkene.

C. Apply the sequence rules to classify alkenes as E or Z isomers.

D. Determine the degree of unsaturation for organic compounds using their molecular formula.

E. Predict the outcome of symmetrical and unsymmetrical addition reactions of alkenes.

F. Correctly define, explain and use the terms and concepts related to alkenes and alkynes.

IV. Alcohols and Ethers

A. Predict trends in physical properties of alcohols, phenols, ethers and thiols based on structure and bond.

B. Name alcohols and ethers using the IUPAC system of naming.

C. Classify alcohols as primary, secondary and tertiary.

D. Describe the condition and the product of oxidation of alcohols.

E. Correctly define, explain and use the terms and concepts related to alcohols and ethers.

V. Aldehydes and Ketones

A. Describe the structure and properties of aldehydes and ketones.

B. Name aldehydes and ketones using the IUPAC system of nomenclature.

C. Propose methods for the preparation of aldehydes and ketones.

D. Predict reactions of aldehydes and ketones.

E. Correctly define, explain and use the terms and concepts related to aldehydes and ketones.

VI. Carboxylic Acids and Esters

A. Name (by IUPAC) and draw structures for both carboxylic acids and esters.

B. Discuss the physical properties of carboxylic acids and esters.

C. Propose synthetic methods for the preparation of carboxylic acids and esters.

D. Predict chemical reactions of esters.

E. Predict polymerization reactions to form polyesters.

F. Correctly define, explain and use the terms and concepts related to carboxylic acids and esters.

VII. Amines and Amides

A. Describe the structure of amines and amides including hybrid orbital overlap and approximate bond angles.

B. Use common or IUPAC prefixes and suffixes to name amines and amides.

C. Classify amines as primary, secondary and tertiary.

D. Predict trends in physical properties of amines based on structure, bond polarity and hydrogen bonding.

E. Describe conditions and predict products of reaction of amines with acids.

F. Predict polymerization reactions to form polyamides.

G. Describe the conditions and predict products for the formation of amides, also the hydrolysis of amides.

H. Correctly define, explain and use the terms and concepts related to amines and amides.

VIII. Carbohydrates

A. Name the monosaccharides having 3 to 6 carbons.

B. Recognize chiral compounds and differentiate between enantiomers and diastereomers.

C. Describe the D and L sugars.

D. Draw the Fischer and Haworth projection for monosaccharides.

E. Describe the process and the results of mutarotation.

F. Describe the oxidation, reduction and formation of glycosides from monosaccharides.

G. Describe the use of Benedict and Tollen's reagents in determining whether a sugar is a reducing or nonreducing sugar.

H. Correctly define, explain and use the terms and concepts related to sugars.

IX. Lipids

A. Describe the common properties of all lipids.

B. Describe the different classes of lipids and list examples of the common classes.

C. Describe the structure, properties and chemical reactions of saturated and unsaturated fatty acids.

D. Describe and draw the formulas for the triglycerides (fats and oils) and phosphoglycerides.

E. Predict trends in physical properties of triglycerides on structure, bond polarity and isomerism.

F. Describe the hydrogenation of oils and the hydrolysis and saponification of triglycerides.

G. Describe the structure and draw formulas for sphingolipids, steroids and waxes.

H. Describe the general structure and the function of lipoproteins.

I. Correctly define, explain and use the terms and concepts related to lipids.

X. Amino Acids, Proteins and Enzymes

A. Describe in detail the general structure of alpha amino acids, including the chirality of the alpha carbon and the zwitterion, types of amino acids based on the side chain change.

B. Describe the relative acidity and basicity of amino acids for different side groups.

C. Describe in detail the peptide bond (amide bond).

D. Describe in detail the primary, secondary, tertiary and quaternary structure of proteins.

E. Describe the effect of change in pH, temperature change and adding specific reagents on protein structure.

F. Use the enzyme classification and naming of enzymes.

G. Discuss the mechanism of enzyme catalysis including the enzyme and substrate complexes, active sites and the rate of reaction.

H. Discuss how the concentration of enzyme or substrate, pH and temperature affects the function of enzyme.

I. Recognize the function of vitamins in enzyme activity.

J. Identify the importance of enzyme activity in metabolic processes.

K. Correctly define, explain and use the terms and concepts related to proteins and enzymes.

XI. Nucleic Acids

A. Identify the different types of nucleotides.

B. Recognize nucleic acid structure.

C. Identify the base pair interactions present in DNA.

D. Outline the steps in replication, transcription and translation.

E. Describe mechanisms that cause mutations.

F. Identify the methods utilized in genetic engineering

G. Correctly define, explain and use the terms and concepts related to nucleic acids, DNA, and RNA.

XII. Attitudes and Work Habits

A. Identify and develop positive attitudes toward tasks and fellow students appropriate for the laboratory, including giving and accepting criticism and praise.

B. Identify and develop productive work habits, including attending to detail, completing tasks, maintaining the work setting and recording data.

C. Identify and develop collaborative/teamwork skills, including solving problems in groups, building consensus and responding to supervision.

Content Outline and Competencies:

I. Teaching as a Career

A. Determine suitability/interest in teaching as a career through thoughtful self-reflection.

B. Explore pathways to a career in teaching.

C. Identify personal learning styles and discuss their implications for classroom interactions.

II. Strategies for Practical Lesson Design

A. Design and deliver inquiry-based hands-on lessons.

B. Write performance objectives for each lesson, including mathematics and/or science connections, and appropriate assessments for those objectives.

C. Use technology and the Internet to enhance classroom lessons, collaborate, and communicate.

III. Concepts and Components of Teaching Theory

A. Identify instructional strategies that meet the needs of diverse learners.

B. Distinguish between learner-centered and teacher-centered instructional strategies.

C. Discuss state and national science and mathematics standards and their implications for curriculum decisions.

D. Identify current issues in the theory and practice of teaching.

IV. Components of a Field Experience

A. Observe a math-science lesson taught by a cooperating teacher.

B. Interact with a population of diverse student learners in a school setting while teaching a lesson in an elementary school classroom.

C. Receive and synthesize feedback from a cooperating teacher as a peer and mentoring colleague in order to improve techniques.

Content Outline and Competencies:

I. Practical Lesson Design

A. Design inquiry-based lessons using the 5E Instructional Model.

B. Write measurable performance objectives for each lesson.

C. Develop applicable pre- and post-assessments for the performance objectives.

D. Analyze student data acquired through pre- and post-assessments to improve future lesson planning.

E. Incorporate technology into at least one lesson in a manner that encourages enhanced student interaction and learning.

II. Teaching Theory

A. Identify instructional approaches that meet the needs of diverse middle school learners.

B. Develop questioning strategies to effectively interact with students with varying abilities and learning styles in a middle school classroom.

C. Develop achievable solutions to preserve instructional equity in the classroom environment.

III. Field Experience

A. Reflect upon observations of lessons taught by an experienced math/science teacher.

B. Teach three inquiry-based lessons to a middle school math or science class.

C. Use probing questions to elicit feedback to determine students’ acquisition of knowledge.

D. Synthesize feedback from both mentor teachers and master teachers in order to improve teaching techniques.

E. Reflect on teaching experiences in order to enhance future classroom interactions.

Content Outline and Competencies:

I. Molecular Structure and Chemical Bonding Theories
   A. Draw Lewis electron dot structures for molecules.
   B. Draw resonance forms for a molecule having delocalized bonding.
   C. Determine the relative stability of resonance forms using formal
charges.
   D. Apply the VSEPR model to describe molecular geometry and shape.
   E. Draw a three-dimensional representation of a given molecule.
   F. Discuss the formation of a covalent bond.
   G. Identify bonds as covalent or ionic. 
   H. Describe the electronic structure of molecules using valence bond
theory.
   I. Predict the hybridization state of atoms in a molecule.
   J. Apply the theory of resonance to show the unusual stability of the
allyl radical and other conjugated pi-bonded species.
   K. Explain the unusual stability of the allyl radical and other
conjugated pi-bonded species in terms of molecular orbital theory.

II. Structure and Properties of Organic Molecules
   A. Predict whether a molecule has a net dipole moment.
   B. Identify the type(s) of intermolecular forces which operate between
molecules.
   C. Predict general trends in boiling points and solubilities based on
intermolecular forces.
   D. Predict relative acidities and basicities based on structure,
bonding and resonance forms of conjugate acid-base pairs.
   E. Predict the direction of Brönsted-Lowry acid-base reactions.
   F. Identify Lewis acids and bases.
   G. Identify by name the following type of compounds (given a condensed
structural formula): alkanes, alkenes, alkynes, aromatic hydrocarbons,
alkyl halides, alcohols, ethers, aldehydes, ketones, carboxylic acids,
esters, amides, amines and phenols.
   H. Draw condensed structural formulas for the following types of
compounds: alkanes, alkenes, alkynes, aromatic hydrocarbons, alkyl
halides, alcohols, ethers, aldehydes, ketones, carboxylic acids, esters,
amides, amines and phenols.

III. Analysis of Organic Reactions
   A. Classify organic reactions as addition, elimination, substitution or
rearrangement.
   B. Distinguish between polar and radical mechanisms.
   C. Identify reagents as electrophiles and nucleophiles.
   D. Apply thermodynamic concepts to the analysis of organic chemical
reactions.
   E. Calculate the enthalpy change for a reaction from a table of bond
energies.
   F. Relate the equilibrium constant for a chemical reaction to the
standard free energy change for that reaction.
   G. Apply qualitative ideas from transition state theory to the analysis
of organic chemical reactions.
   H. Draw and interpret an energy diagram for a chemical reaction.
   I. Discuss the meaning of the term activation energy.

IV. Nomenclature
   A. Given the structure, provide correct IUPAC names for alkanes,
cycloalkanes, alkenes,   alkynes, dienes and alkyl halides.
   B. Given the name, draw correct condensed structural formulas for
alkanes,
cycloalkanes, alkenes, alkynes, dienes and alkyl halides.
   C. Draw and use common names for all 3- and 4-carbon alkyl groups.

V. Alkanes and Cycloalkanes
   A. Name and draw structures for alkanes and cycloalkanes by the IUPAC
system.
   B. Identify carbon and hydrogen as being primary, secondary or
tertiary.
   C. Draw all possible isomers given the molecular formula.
   D. Draw Newman projections of different conformations of molecules and
predict their relative stability.
   E. Discuss the applicability of Bayer strain theory to the stabilities
of cycloalkanes.
   F. Compare and contrast the terms ring and angle strain.
   G. Draw structures for both boat and chair cyclohexane.
   H. Distinguish (by drawing) the difference between axial and equatorial
positions in
cyclohexane.
   I. Recognize cis and trans isomers of disubstituted cyclohexanes.
   J. Predict the stability of substituted cyclohexanes by estimating
steric interactions.

VI. Alkenes, Alkynes and Conjugated Dienes
   A. Name and draw structures for alkenes and alkynes by the IUPAC
system.
   B. Determine the degrees of unsaturation of an organic compound from
its molecular formula.
   C. Discuss the bonding and electronic structure of alkenes.
   D. Draw and name cis-trans isomers of alkenes.
   E. Apply the sequence rules to classify alkenes as E or Z isomers.
   F. Use heats of hydrogenation to determine the relative stability of
alkenes.
   G. Show by reaction the preparation of alkenes, alkynes and conjugated
dienes.
   H. Predict the products of reactions of alkenes, alkynes and conjugated
dienes.
   I. Discuss the bonding and electronic structure of alkynes.
   J. Compare and contrast the reactions of alkenes and alkynes.
   K. Explain why the terminal hydrogen in terminal alkynes is acidic.
   L. Explain the unusual stability of conjugated dienes.

VII. Alkyl Halides
   A. Name and draw structures for alkyl halides by the IUPAC system.
   B. Show by reaction the preparation of  alkyl halides.
   C. Predict the products of reactions of alkyl halides.

VIII. Stereochemistry
   A. Recognize the difference between constitutional isomers and
stereoisomers.
   B. Determine if an object or molecule is chiral.
   C. Apply the RS system of nomenclature to stereoisomers.
   D. Compare and contrast, using examples if necessary, the following
terms: enantiomers,
diasteromers and meso compounds.
   E. Draw Fischer projections of chiral compounds.
   F. Explain the difference between relative and absolute
configurations.
   G. Predict the theoretical number of stereoisomers.
   H. Predict the stereochemical outcome of selected reactions.

IX. Substitution and Elimination Reactions
   A. Discuss the kinetics involved with nucleophilic substitution
reactions.
   B. Classify reactions as SN1, SN2, E1 or E2.
   C. List a set of ideal conditions for SN1, SN2, E1 or E2 reactions.
   D. Discuss the factors that can influence the rates of SN1, SN2, E1 or
E2 reactions.
   E. Predict the products of  SN1, SN2, E1 or E2 reactions.
   F. Explain the limitations placed upon elimination reactions that
involve the cyclohexane ring.

X. Mechanisms
   A. Draw and explain the radical mechanism for the halogenation of
alkanes.
   B. Explain the relationship of the structure of free radicals to
stability.
   C. Draw and discuss each step of the mechanism of an alkene addition
reaction.
   D. Explain the relationship of carbocation structure to stability.
   E. Recognize when carbocation rearrangement is likely to occur.
   F. Apply the Hammond postulate to the analysis of a reaction
mechanism.
   G. Draw and explain the mechanism for a SN1, SN2, E1 or E2 reaction.
   H. Compare and contrast kinetic and thermodynamic control of 1,2- and
1,4-addition reactions of conjugated dienes.

XI. Spectral Interpretation
   A. Identify functional groups by their infrared absorptions.
   B. Correlate the infrared spectrum of a known organic compound to its
structure.
   C. Propose a structure for an unknown consistent with its infrared
spectrum and other data such as the molecular formula.

XII. Critical Thinking
   A. Devise a reasonable synthetic pathway for producing a desired
compound from a specific starting material.
   B. Propose a reaction mechanism to explain the outcome of a reaction
you have never seen before.
   C. Determine the structure of an unsaturated compound from its
molecular formula and its cleavage and/or hydrogenation products.

XIII. Students Will Work in the Laboratory in Accordance with Good
Laboratory Practices
   A. Dress appropriately on lab days, wearing long pants and shoes with
enclosed toes, and wear a lab coat and goggles when anyone in the
laboratory is using chemicals.
   B. Follow written directions accurately.
   C. Work safely, using equipment and chemicals carefully and correctly.
   D. Obtain samples from stock reagents that are the correct substance,
concentration and sample size.
   E. Dispose of waste products appropriately.

XIV. Students Will Gather and Record Qualitative and Quantitative Data
   A. Record data in a concise and accurate fashion, reporting visual
observations, such as color, state and speed of reaction.
   B. Demonstrate required techniques, which include:
      1. Assembly of microscale glassware
      2. Use of milligram balance
      3. Use of automatic pipet
      4. Monitoring and controlling the temperature of a reaction vessel
      5. Filtration
      6. Crystallization
      7. Determination of melting point and boiling point
      8. Extraction
      9. Use of drying agents
     10. Reflux
     11. Simple and fractional distillation
     12. Thin-layer chromatography
     13. Column chromatography
     14. Gas chromatography
     15. Refractometry
     16. Infrared sample preparation
     17. Operation of infrared spectrometer
   C. List or describe experimental assumptions made.

XV. Students Will Handle and Evaluate Data in Meaningful Ways
   A. Create notebooks and laboratory reports that are clear,
understandable and accurately represent the work done.
   B. Correlate observations with appropriate chemical and/or physical
processes.
   C. Carry out suitable calculations with quantitative data, recognizing
when data and calculations are within a reasonable range.
   D. Use applicable theories to draw experimental conclusions and explain
observations.

All exams will be taken in class (no take home exams will be given)
 
 40% of grade         3-6 Unit Exams                  
 20% of grade         Final Exam             
 10% of grade         Quizzes and/or Homework      
 30% of grade         Laboratory    
100%

Grading Scale:
   90% - 100% = A
   80% -  89% = B
   70% -  79% = C
   60% -  69% = D
    0% -  59% = F

Content Outline and Competencies:

Content Outline and Competencies:

I. Structure Determination by Spectroscopy
   A. Mass spectroscopy
      1. Use mass spectroscopy data to interpret molecular structure.
      2. Interpret mass spectral fragmentation patterns.
      3. Use mass spectra to determine molecular weights and base peaks
and to distinguish between hydrocarbons.
      4. Write molecular formulas corresponding to a given molecular ion.
   B. Infrared spectroscopy
      1. Identify the regions of the electromagnetic spectrum used for
infrared spectroscopy.
      2. Relate energy, frequency and wavelength for electromagnetic
radiation to infrared spectroscopy.
      3. Interpret infrared spectra relating to functional groups in
organic molecules.
      4. Interpret infrared spectra for hydrocarbons.
   C. Nuclear magnetic resonance spectroscopy
      1. Describe how NMR signals are obtained.
      2. Interpret chemical shift patterns relating to chemical
structure.
      3. Interpret 1H NMR peak areas using integration techniques in
relationship to proton counting.
      4. Use spin-spin splitting of 1H NMR signals to interpret molecular
structure in organic molecules.
      5. Relate and use the number of 1H NMR absorptions to proton
equivalency in a molecule.
      6. Relate and use chemical shifts in 1H NMR spectroscopy to
determine chemical structure in organic molecules.
      7. Use 1H NMR spectra to determine the chemical structure of a
compound.
      8. Interpret 13C NMR spectroscopy relating to functional groups in
organic molecules.
      9. State the uses of 1H NMR spectra.   

II. Benzene and Aromaticity
   A. State sources of aromatic hydrocarbons.
   B. Name by IUPAC and draw structures for aromatic compounds.
   C. Recognize and be able to use the names and structures for toluene,
phenol, aniline,
acetophenone, benzaldehyde and benzoic acid.
   D. Explain how Kekule accounted for the unusual properties of benzene.
   E. Use thermodynamic data to show that benzene is more stable than the
hypothetical compound 1,3,5-cyclohexatriene.
   F. Compare the reactivity of benzene to cyclohexene.
   G. List the four postulates of resonance theory.
   H. Use molecular orbital (MO) theory to describe the bonding in benzene
and other aromatic compounds.
   I. Relate aromaticity to Huckel's rule and MO theory.
   J. Predict aromaticity of heterocylic compounds.
   K. Predict aromaticity of ions.
   L. Describe the bonding in polycyclic aromatic hydrocarbons.
   M. Identify the spectroscopic regions of the IR for aromatic compounds
for use in structural determination of organic molecules.

III. Chemistry of Benzene:  Electrophilic Aromatic Substitution
   A. Draw and explain the general mechanism for electrophilic aromatic
substitution.
   B. Predict the products and/or write mechanisms for electrophilic
aromatic substitution reactions studied.
   C. Use the above listed reactions in synthesis.
   D. Explain how substituents affect the reactivity of aromatic rings.
   E. Discuss ortho-para and meta directors, giving some characteristics
and examples of each.
   F. Predict the orientation of incoming groups in disubstituted benzene
rings.
   G. Predict the orientation of incoming groups in trisubstituted benzene
rings.
   H. Recognize the conditions necessary for nucleophilic aromatic
substitution to occur.
   I. Draw and explain the addition-elimination mechanism and the
elimination-addition mechanism in nucleophilic aromatic substitution
reactions.
   J. Use oxidation reactions of aromatic compounds.
   K. Use reduction reactions of aromatic compounds.
   L. Identify the difference in reactivity between the aromatic ring and
a substituted side-chain in oxidation and radical bromination reactions.
   M. Use the reactions learned for electrophilic aromatic substitution to
work synthesis problems.

IV. Alcohols and Thiols
   A. Name by IUPAC and draw structures for alcohols.
   B. Identify sources and uses of simple alcohols.
   C. Compare the physical properties of alcohols to alkanes and alkyl
halides.
   D. Show how to use acid-base reactions to prepare alkoxide ions.
   E. Show how alcohols are prepared from alkenes, aldehydes, ketones,
esters and carboxylic acids.   
   F. Prepare alcohols from reduction of carbonyl groups.
   G. Show how the Grignard reaction can be used to make 1o , 2 o or 3 o
alcohols.
   H. Describe the limitations of the use of the Grignard reaction in
synthesis or organic compounds.
   I. Show how alkenes, alkyl halides and tosylates can be prepared from
alcohols.
   J. Show how alcohols may be oxidized to carbonyl compounds.
   K. Use the alcohol reactions studied in synthesis reactions.
   L. Discuss the use of protecting groups in organic synthesis.
   M. Identify the spectroscopic regions of the IR for alcohols for use in
structural determination of organic molecules.
   N. Describe the similarities of thiols to alcohols.

V. Ethers, Epoxides and Sulfides
   A. Name by IUPAC and draw structures for ethers.
   B. Compare the physical properties of ethers to alkanes of comparable
molecular weights.
   C. Describe the industrial preparation of ethers.
   D. Prepare ethers via the Williamson ether synthesis.
   E. Prepare ethers via alkoxymercuration-demercuration of alkenes.
   F. Predict the products formed in an acid-induced cleavage of an
ether.
   G. Name cyclic ethers:  epoxides.
   H. Show by equations how epoxides are produced.
   I. Show the mechanism and predict the product formed (with correct
stereochemistry) in the acid-catalyzed and base-catalyzed ring opening
reactions of epoxides.
   J. Use the ether and epoxide reactions studied in synthesis.
   K. Discuss the use of crown ethers in organic synthesis.
   L. Identify the Spectroscopic regions of the IR for ethers and epoxides
for use in structural determination of organic molecules.
   M. Describe the similarities of Sulfides to ethers.

VI. Aldehydes and Ketones:  Nucleophilic Addition Reactions
   A. Compare the physical properties of aldehydes and ketones to alkanes
and alcohols of comparable molecular weights.
   B. Name by IUPAC and draw structures for aldehydes and ketones.
   C. Recognize and use the following common names: formaldehyde,
acetaldehyde and ketones.
   D. Show the general mechanism for nucleophilic addition at the carbonyl
group.
   E. Show by equations the preparation of aldehydes and ketones.
   F. Show by reactions how aldehydes and ketones react with oxidizing and
reducing agents.
   G. Predict the products of nucleophilic addition reactions with a
variety of reagents studied for aldehydes and ketones.
   H. Use the above listed reactions in synthesis.
   I. Identify the spectroscopic regions of the IR for aldehydes and
ketones for use in structural determination of organic molecules.

VII. Carboxylic Acids
   A. Name by IUPAC and draw structures for both mono and dicarboxylic
acids.
   B. Recognize and use the following common names: formic acid, acetic
acid, benzoic acid and oxalic acid.
   C. Discuss the structure and physical properties of carboxylic acids.
   D. Discuss the acidity of carboxylic acids and the factors that affect
the stability of the carboxylate anion.
   E. Discuss substituent effects on acidity of benzoic acids and
substituted benzoic acids.
   F. Show by equations the preparation of carboxylic acids.
   G. Predict the products of reactions of carboxylic acids.
   H. Predict the products of reduction of carboxylic acids to primary
alcohols.
   I. Use the carboxylic reactions studied in synthesis.
   J. Identify the spectroscopic regions of the IR for carboxylic acids
for use in structural determination of organic molecules.

VIII. Carboxylic Acid Derivatives and Nucleophilic Acyl Substitution
Reactions
   A. Name by IUPAC convention and draw structures for acid halides, acid
anhydrides, amides, esters and nitriles.
   B. Recognize and use the following common names: acetyl chloride,
acetic anhydride, acetamide and acetonitrile.
   C. Show the general mechanism for nucleophilic acyl substitution.
   D. Predict the products of carboxylic acid derivative reactions.
   E. Predict the products of nucleophilic acyl substitution reactions of
carboxylic acid derivatives studied and be able to use those reactions in
synthesis problems.
   F. Use the carboxylic acid derivative reactions studied in synthesis.
   G. Identify the spectroscopic regions of the IR for carboxylic acid
derivatives for use in structural determination of organic molecules.

IX. Carbonyl Alpha-Substitution Reactions
   A. Show keto-enol tautomerism in carbonyl compounds.
   B. Show how tautomerism differs from resonance.
   C. Illustrate the mechanism of alpha-substitution reactions.
   D. Predict the products of carbonyl alpha-substitution reactions
studied and be able to use those reactions in synthesis.     
   E. Describe the acidity of alpha-hydrogen atoms:  enolate ion
formation.
   F. Predict the reactivity of enolate ions.

X. Carbonyl Condensation Reactions
   A. Show the general mechanism of carbonyl condensation reactions.
   B. Predict the products of condensation reactions of aldehydes and
ketones:  the aldol reaction.
   C. Describe the difference of carbonyl condensation reactions versus
alpha-substitution reactions.
   D. Identify aldol products.
   E. Identify mixed aldol products.
   F. Identify intramolecular aldol products.
   G. Predict the products of reactions studied that are similar to the
aldol condensation reaction.
   H. Use the condensation reactions studied in synthesis.
   
XI. Carbohydrates
   A. Classify carbohydrates by the number of carbons, presence and size
of ring, and type of glycoside linkage.
   B. Draw Fischer projections for depicting carbohydrates.
   C. Use the DL sugars nomenclature system.
   D. Draw monosaccharides in the various representations studied and be
able to convert from one representation to another.
   E. Convert from straight chain to the cyclic hemiacetal formation for
monosaccharides.
   F. Explain mutarotation in sugars.
   G. Explain why some sugars are reducing and others are not.
   H. Predict the products of reactions studied of monosaccharides.
   I. Explain the Fischer Proof.
   J. List simple disaccharides.
   K. Discuss the similarities and differences of the polysaccharides
starch and cellulose.

XII. Aliphatic Amines
   A. Name by IUPAC and draw structures for amines.
   B. Discuss structure and bonding in amines.
   C. Relate physical properties of amines to structure.
   D. Discuss basicity of amines in terms of their structure.
   E. Compare the basicity of amines to amides.
   F. State industrial sources and uses of alkylamines.
   G. Show by equations reactions of amines.
   H. Use reactions to synthesize amines.
   I. Identify the spectroscopic regions of the IR for amines for use in
structural determination of organic molecules.

XIII. Arylamines and Phenols
   A. Explain why alkyl amines are more basic than arylamines.
   B. Show how to prepare arylamines.
   C. Predict the products of reactions of arylamines.   
   D. Use the replacement reactions of arenediazonium salts in synthesis.
   E. Show how diazonium salts can be used in coupling reactions.
   F. State industrial uses of phenols.   
   G.  Explain the acidity of phenols in terms of their structure.
   H. Show by reactions the preparation of phenols.
   I. Predict the products of reactions of phenols.
   J. Use reactions of phenols to solve synthesis problems.
   K. Recognize the spectroscopic regions of the IR for arylamines and
phenols for use in structural determination of organic molecules.

XIV.  Laboratory 
   A. Record data in a concise and accurate manner, reporting visual
observations such as color, physical states and temperature conditions.
   B. Correctly demonstrate required techniques, which include:
      1. Use of the laboratory balance
      2. Use of an automatic pipette
      3. Use of a heating plate with a heating block or sand bath to
monitor the temperature of a reaction
      4. Use of filtration equipment
      5. Use of equipment for crystallization and recrystallization
techniques
      6. Use of melting point apparatus to determine melting points of
organic compounds
      7. Use of equipment to determine the boiling points of organic
liquids
      8. Use of drying agents
      9. Use of equipment for reflux of reaction mixtures
     10. Use of distillation equipment
     11. Use of chromatography techniques for compound identification
     12. Use of FTIR to prepare samples and obtain spectra of organic
compound
   C. List and/or describe experimental assumptions made.
   D. Dress appropriately on lab days, which includes wearing long pants
or skirts, enclosed toes, lab coat and goggles.
   E. Follow written directions accurately.
   F. Work safely using equipment and chemicals safely and appropriately.
   G. Obtain stock reagents correctly.
   H. Dispose of waste products according to chemical hygiene guidelines.
   I. Create notebooks and laboratory reports according to written
guidelines.
   J. Correlate observations with appropriate chemical and/or physical
processes.
   K. Make calculations with the data collected, recognizing  calculations
that do not fall within reasonable ranges.
   L. Use applicable theories learned in lecture to draw experimental
conclusions and explanations of observations.  

All exams will be taken in class (no take home exams will be given)
 
 40% of grade        3-6 Unit Exams                   
 20% of grade        Final Exam        
 10% of grade        Quizzes and/or Homework       
 30% of grade        Laboratory              
100%

Grading Scale:
   A = 90% - 100%
   B = 80% -  89%
   C = 70% -  79%
   D = 60% -  69%
   F =  0%  - 59%

Content Outline and Competencies:

Content Outline and Competencies:

I. Investigate the Properties of Water and the Application of Aqueous
Solutions to Biochemical Systems
   A. Compare and contrast the different types of intermolecular forces.
   B. Describe the different types of acids and bases.
   C. Cite examples of buffer systems.
   D. Calculate pH and composition of buffers using the
Henderson-Hasselbach equation.
   E. Describe the effects of changes in pH on the uptake and release of
O2 and CO2 in red blood cells.

II. Describe the Structures and Functions of Amino Acids and Small
Peptides
   A. Classify amino acid structures according to ionic properties and
polarity.
   B. Investigate the stereochemistry of amino acids.
   C. Predict the acid-base characteristics of amino aids and peptides.
   D. Investigate the reactions and functions of small peptides and amino
acids.

III. Explain Aspects of Protein Structure
   A. Compare and contrast the four levels of protein structure.
   B. Describe different protein purification techniques.
   C. Determine the most appropriate chromatography method for a given set
of circumstances.
   D. Determine the primary structure of polypeptides from a set of data.
   E. Compare and contrast the different types of secondary structure.
   F. Describe the structure and functions of collagen.
   G. Summarize the tertiary structure of proteins.
   H. Compare and contrast differences in the structure and functions of
Hb and Mb.
   I. Relate the quaternary structure of Hb to cooperative binding of O2.
   J. Describe the effects of bisphosphoglycerate on Hb and Mb.

IV. Examine the Properties of Enzymes
   A. Classify major classes of enzymes.
   B. Correlate the relationship between free energy, catalysts and
kinetics.
   C. Interpret enzyme kinetics according to the Michaelis-Menton scheme.
   D. Determine the effects of inhibitors and activators on Km and Vmax
values.
   E. Describe allosterism and allosteric enzymes.
   F. Compare and contrast the concerted and sequential models for
allosteric enzymes.
   G. Describe zymogen activation.
   H. Explain the different modes of catalytic action in enzymes.
   I. Draw the mechanism for serine proteases.
   J. Classify coenzymes.

V. Describe the Structures and Functions of Lipids and Biological
Membranes
   A. Compare and contrast different classes of lipids.
   B. Describe the structures and properties of fatty acids.
   C. Describe the structures and functions of steroids.
   D. Explain the synthesis of eicosanoids.
   E. List the functions of eicosanoids.
   F. Compare and contrast the functions of the lipid soluble vitamins.
   G. Detail the reactions of the action of vitamin A in the process of
vision.
   H. Describe the composition and structure of membranes.
   I.    Compare and contrast the methods of membrane transport.
   J. Detail the action of the Na+, K+-ATPase.
   K. Describe enzyme receptors and the action of the insulin receptor.

VI. Describe the Structures and Functions of Carbohydrates
   A. Describe the structures of common monosaccharides and
disaccharides.
   B. Compare and contrast the structures and functions of
polysaccharides.

VII. Relate Principles of Thermodynamics to Biological Systems
   A. Relate thermodynamic properties to equilibrium and spontaneity of
chemical reactions.
   B. Calculate the change in free energy for systems not at equilibrium
and not at standard conditions.
   C. Calculate the ?GEN from equilibrium constant data (or an equilibrium
constant from ?GEN data).
   D. Calculate the ?GEN from standard reduction potentials.
   E. List high energy groups utilized in metabolism.
   F. Compare and contrast catabolic and anabolic pathways in metabolism.

VIII. Describe the Pathways Involved with Carbohydrate Metabolism
   A. Write the reactions of glycolysis.
   B. Discuss the energetics involved with glycolysis.
   C. Describe the regulation of glycolysis including activators and
inhibitors of the major regulatory enzymes.
   D. Write the reactions involved with glycogen metabolism.
   E. Describe the control of glycogen metabolism including the effect of
the c-AMP cascade.
   F. Write the reactions involved with gluconeogenesis.
   G. Describe how glucagon can affect the control of the reactions of
glycolysis and
gluconeogenesis in liver cells.
   H. Describe the major products of the pentose phosphate shunt and write
the overall reaction of the pathway.
   I. Detail the steps involved with the reaction of pyruvate in the
pyruvate dehydrogenase complex.
   J. Describe the regulation of the pyruvate dehydrogenase complex
including the   activators and inhibitors of enzymes in the complex.
   K. Write the reactions of the citric acid cycle.
   L. Describe the regulation of the citric acid cycle including
activators and inhibitors of the major regulatory enzymes.
   M. Write the reactions involving the entry and exit of metabolites into
and out of the citric acid cycle.
   N. Describe the major reactions occurring in the compartments of the
mitochondria.
   O. Write the reactions of the electron transport system.
   P. Describe the effects that uncouplers and inhibitors of oxidative
phosphorylation have on the production of ATP.
   Q. Describe the chemiosmotic coupling theory and its relationship to
the generation of ATP.
   R. Describe how a proton gradient can be utilized by the ATPase to
drive the production of ATP.
   S. Write the reactions required to oxidize NADH in the cytoplasm under
aerobic conditions.
   T. Explain how the action of cytochrome P450 is involved with oxidation
reactions occurring in the liver.

IX. Describe the Processes Involved in the Light Reactions of
Photosynthesis
   A. Describe the major reactions occurring in the compartments of the
chloroplast.
   B. Describe the photochemical pigments found in the antenna complex.
   C. Explain the role of carotenoids in photoprotection for
photosynthesis.
   D. Explain the steps involved in the principal photochemical events in
the light reactions of photosynthesis.
   E. Write the products of the Z-scheme of the light reactions of
photosynthesis.

X. Describe the Reactions Involved with Lipid Metabolism
   A. Compare and contrast the types of lipoproteins.
   B. Write the reactions involved in the transport of fatty acids into
the mitochondria.
   C. Write the reactions for the catabolism of saturated fatty acids.
   D. Calculate the number of ATP produced from the complete oxidation of
a fatty acid.
   E. Write the reactions for the formation of ketone bodies.
   F. Write the reactions involved with transporting acetyl-SCoA from the
mitochondria to the cytoplasm.
   G. Write the reactions involved with fatty acid synthesis.
   H. Describe the synthesis of the phospholipids and cholesterol.

XI. Describe Reactions Involved with Amino Acid Metabolism
   A. Describe the nitrogen cycle and the reactions of the nitrogenase
complex.
   B. List the ketogenic and glycogenic amino acids.
   C. Draw the mechanism for transamination reactions.
   D. Write the overall reaction of the urea cycle.

XII. Explain Aspects of the Structure of Nucleic Acids
   A. Compare and contrast the structures of purines and pyrimidines.
   B. Describe the structures of nucleotides and nucleosides.
   C. List Chargaff's rules as they apply to the primary structure of
DNA.
   D. Describe the secondary structure of B form DNA.
   E. Compare and contrast the structures of B form DNA and Z form DNA.
   F. Describe the tertiary structures of DNA.
   G. Determine the linking number associated with a piece of DNA.

XIII. Describe the Processes Associated with the Central Dogma Theory of
Molecular Biology
   A. Diagram the central dogma theory of molecular biology.
   B. Describe the processes required to sequence a piece of DNA.
   C. Discuss the experiments which show that replication is
semiconservative.
   D. Describe the processes and reactions necessary to replicate DNA.
   E. Compare and contrast different types of mutations in DNA.
   F. Describe repair mechanisms for DNA.
   G. List the requirements for transcribing a piece of DNA.
   H. Describe the processes and reactions necessary for transcription.
   I. Discuss post-transcriptional modifications of RNA.
   J. Discuss regulation of transcription and the Lac Operon.
   K. Interpret the universal genetic code.
   L. Describe the structures of t-RNA and r-RNA.
   M. Describe the processes and reactions necessary for translation.
   N. List post-translational modifications of proteins.
 
XIV. Describe the Experimental Basis for Recombinant DNA Technology
   A. Describe the experimental procedures for introducing a recombinant
into a host cell.

Examinations/projects      60-70% of grade
Quizzes                    10-20% of grade
Final exam                    20% of grade
       Total                 100%

Final grades will be determined with the following percentage scores based
upon the total number of points obtained:
   A = 90% - 100%
   B = 80% -  89%
   C = 70% -  79%
   D = 60% -  69%
   F =  0% -  59%